Clinicopathological evaluation of focal reactive lesions of the Gingiva
DOI:
https://doi.org/10.17159/2519-0105/2021/v76no8a3Keywords:
Focal reactive gingival lesions, pyogenic granuloma, lobular capillary haemangioma. Peripheral ossifying fibroma, focal fibrous hyperplasia and peripheral giant cell granuloma.Abstract
Focal reactive gingival lesions are elicited by chronic irritation primarily due to dental plaque, calculus, overhanging dental restorations and ill-fitting dental prosthesis. Persistent irritation of the gingiva can lead to tissue injury and trigger inflammation leading to proliferation of endothelial cells, multi-nucleated giant cells, fibroblasts and tissue mineralisation. The aim and objectives of the study were to determine the relative frequency and distribution of focal reactive gingival lesions according to sex, age, and anatomical site in patients who presented at the Witwatersrand Oral Health Centre. Retrospective cross-sectional study Methods Convenience sampling of patient records from the years 2011 to 2017 were analysed from the Department of Oral Pathology and the Department of Oral Medicine and Periodontology at the Witwatersrand Oral Health Centre. Sociodemographic variables and clinical features were evaluated. Female patients accounted for 70.8% (n = 172) of all focal reactive gingival lesions, with the majority of the lesions having occurred in the maxilla (56.4%; n = 137). The age of patients ranged from 3 months to 88 years. Contrary to findings in other studies, the peripheral ossifying fibroma was the most common focal reactive gingival lesion, after analysing 243 cases
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Zarei MR, Chamani G, Amanpoor S. Reactive hyperplasia of the oral cavity in Kerman province, Iran: A review of 172 cases. Br J Oral Maxillofac Surg. 2007;45(4):288–92.
Dutra KL, Longo L, Grando LJ, Rivero ERC. Incidence of reactive hyperplastic lesions in the oral cavity: a 10 year retrospective study in Santa Catarina, Brazil. Braz J Otorhinolaryngol. 2019;85(4):399–407.
Reddy V, Saxena S, Saxena S, Reddy M. Reactive hyperplastic lesions of the oral cavity: A ten year observational study on
North Indian population. J Clin Exp Dent. 2012;4(3):136–40.
Kamal R, Dahiya P, Puri A. Oral pyogenic granuloma: Various concepts of etiopathogenesis. J Oral Maxillofac Pathol. 2012;16(1):79–82.
Peralles PG, Viana APB, Azevedo AL da R, Pires FR. Gingival and alveolar hyperplastic reactive lesions: clinicopathological study of 90 cases. Braz j oral sci. 2006;5(18):1085–9.
Neville BW, Damm DD, Allen CM, Chi A. Oral and maxillofacial pathology. 4th ed. Philadelphia: W.B. Saunders; 2002. 473-526.
Effiom OA, Adeyemo WL, Soyele OO. Focal Reactive lesions of the Gingiva: An Analysis of 314 cases at a tertiary Health Institution in Nigeria. Niger Med J. 2011;52(1):35–40.
Prasad S, Reddy SB, Patil SR, Kalburgi NB, Puranik RS.
Kumar SKS, Ram S, Jorgensen MG, Shuler CF, Sedghizadeh PP. Multicentric peripheral ossifying fibroma. J Oral Sci. 2006;48(4):239–43.
Rossmann JA. Reactive Lesions of the Gingiva: Diagnosis and Treatment Options. Open Pathol J. 2011;5(1):23–32.
Buchner A, Hansen LS. The histomorphologic spectrum of peripheral ossifying fibroma. Oral Surgery, Oral Med Oral Pathol.
;63(4):452–61.
Kenney JN, Kaugars GE, Abbey LM. Comparison between the peripheral ossifying fibroma and peripheral odontogenic fibroma.
J Oral Maxillofac Surg. 1989;47(4):378–82.
Miller CS, Henry RG, Damm DD. Proliferative Mass Found in the Gingiva. J Am Dent Assoc. 1990;121(4):559–60.
Günhan M, Günhan Ö, Celasun B, Mutlu M, Bostanci H. Estrogen and progesterone receptors in the peripheral giant cell granulomas of the oral cavity. J Oral Sci. 1998;40(2):57–60.
Tamiolakis P, Chatzopoulou E, Frakouli F, Tosios KI, SklavounouAndrikopoulou A. Localized gingival enlargements. A clinicopathological study of 1187 cases. Med Oral Patol Oral y Cir Bucal. 2018;23(3):320–5.
Maturana-Ramírez A, Adorno-Farías D, Reyes-Rojas M, Farías-Vergara M, Aitken-Saavedra J. A retrospective analysis of reactive hyperplastic lesions of the oral cavity: study of 1149 cases diagnosed between 2000 and 2011, Chile. Acta Odontol Latinoam. 2015;28(2):103–7.
Dawes C. Why does supragingival calculus form preferentially on the lingual surface of the 6 lower anterior teeth?. J Can Dent Assoc. 2006,72(10):923-6.
Agrawal AA. Gingival enlargements: Differential diagnosis and review of literature. World J Clin Cases. 2015;3(9):779–88.
Bodner L, Dayan D. Growth potential of peripheral ossifying fibroma. J Clin Periodontol. 1987;14(9):551–4.
Salum FG, Yurgel LS, Cherubini K, De Figueiredo MAZ, Medeiros IC, Nicola FS. Pyogenic granuloma, peripheral giant cell granuloma and peripheral ossifying fibroma: retrospective analysis of 138 cases. Minerva Stomatol. 2008;57(5):227–32.
Babu B, Hallikeri K. Reactive lesions of oral cavity: A retrospective study of 659 cases. J Indian Soc Periodontol. 2017;21(4):258–63.
Pearson GJ, Schuckert KH. The role of lasers in dentistry: present and future. Dent Update. 2003;30(2):70-4.
Kfir Y, Buchner A, Hansen LS. Reactive lesions of the gingiva. A clinicopathological study of 741 cases. J Periodontol. 1980;51(1):655-61.
Naderi NJ, Eshghyar N, Esfehanian H. Reactive lesions of the oral cavity: A retrospective study on 2068 cases. Dent Res J (Isfahan). 2012;9(3):251–5.
Zhang W, Chen Y, An Z, Geng N. Reactive gingival lesions: A retrospective study of 2,439 cases. Quintessence Int (Berl). 2007;38(1):103–10.
Macleod RI, Soames J V. Epulides: A clinicopathological study of a series of 200 consecutive lesions. Br Dent J. 1987;163(2):51–3.
Shamim T, Varghese V, Shameena P, Sudhas S. A retrospective analysis of gingival biopsied lesions in south indian population. Med Oral Patol Oral y Cir Bucal. 2008;13(1):441–8.
Mishra MB, Bhishen KA, Mishra S. Peripheral ossifying fibroma. J Oral Maxillofac Pathol. 2011;15(1):65–8.
Shetty D, Urs A, Ahuja P, Sahu A, Manchanda A, Sirohi Y. Mineralized components and their interpretation in the histogenesis of peripheral ossifying fibroma. Indian J Dent Res. 2011;22(1):56–61.
Kashyap B, Reddy Ps, Nalini P. Reactive lesions of oral cavity: A survey of 100 cases in Eluru, West Godavari district. Contemp
Clin Dent. 2012;3(3):294–7.
Buchner A, Shnaiderman-Shapiro A, Vered M. Relative frequency of localized reactive hyperplastic lesions of the gingiva: a retropective study of 1675 cases from Israel. J Oral Pathol Med. 2010;39(8):631–8.
Anneroth G, Sigurdson A. Hyperplastic lesions of the gingiva and alveolar mucosa: A study of 175 cases. Acta Odontol Scand.
;41(2):75–86.
Daley TD, Nartey NO, Wysocki GP. Pregnancy tumor: An analysis. Oral Surgery, Oral Med Oral Pathol. 1991;72(2):196–9.
Eversole LR, Rovin S. Reactive lesions of the gingiva. J Oral Pathol. 1972;1(1):30-8.
Oliveira ML aur. C, Wagner VP eterse., Sant’ana Filho M, Carrard VC oelh., Hugo FN eve., Martins MD omingue. A 10-year analysis
of the oral squamous cell carcinoma profile in patients from public health centers in Uruguay. Braz Oral Res. 2015;29(1):1–8.
Mergoni G, Meleti M, Magnolo S, Giovannacci I, Corcione L, Vescovi P. Peripheral ossifying fibroma: A clinicopathologic study
of 27 cases and review of the literature with emphasis on histomorphologic features. J Indian Soc Periodontol. 2015;19(1):83–7.
Patil S, Somashekar S, Wadhawan R, Deoghare A, Khandelwal S, Maheshwari S. Prevalence of reactive hyperplastic lesions of the gingiva in the Western Indian population. J Orofac Sci. 2014;6(1):41.
Kazmi F, Alamgir W, Mumtaz M. Diagnostic Challenges in assesement of reactive soft tissue lesions of oral cavity. Int J Cur Res Rev. 2015;7(10):79–86.
Kohli K, Christian A, Howell R. Peripheral ossifying fibroma associated with a neonatal tooth: case report. Pediatr Dent. 1998;20(7):428–9.
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