Resolution of a large periapical lesion in an immature maxillary lateral incisor with the aid of triple antibiotic paste

Authors

  • Nicoline Potgieter Department of Paediatric Dentistry, Faculty of Dentistry, University of the Western Cape https://orcid.org/0000-0003-4061-3322
  • Glynn Buchanan Department of Odontology, School of Dentistry, Faculty of Health Sciences, University of Pretoria

DOI:

https://doi.org/10.17159/2519-0105/2021/v76no9a7

Keywords:

apexification, endodontics, triple antibiotic paste, calcium hydroxide

Abstract

Apexification procedures are frequently performed on immature permanent teeth with incomplete root formation, open apices and necrotic pulp status with or without  periapical lesions in order to induce a calcific barrier prior to root canal therapy. The elimination and control of infection in the root canal space is critical to the success of these procedures. A healthy 21-year old male presented with pulpal necrosis, a large periapical lesion, incomplete root formation and an open apex on a maxillary right lateral incisor. Triple antibiotic paste was used to achieve antimicrobial control after traditional calcium hydroxide paste medicament failed to resolve
the symptoms. Obturation was achieved using MTA and the conventional apexification technique. Excellent healing of the large periapical lesion was achieved without surgical intervention and the 4-year follow-up CBCT demonstrated complete bone fill of the lesion. Clinicians should be aware that alternative antimicrobial medicaments, such as triple antibiotic paste, may be
beneficial in situations where conventional medicaments prove unsuccessful. The use of triple antibiotic paste may result in sufficient healing of the periapical lesion to justify placement of an MTA apical barrier without the need for surgical intervention

Downloads

Download data is not yet available.

Author Biography

  • Nicoline Potgieter, Department of Paediatric Dentistry, Faculty of Dentistry, University of the Western Cape



References

Shabahang S. Treatment options: Apexogenesis and apexification. Pediatr Dent. 2013; 35: 125–8. DOI: https://doi.org/10.1016/j.joen.2012.11.046

Sheely E, Roberts G. Use of calcium hydroxide for apical barrier formation and healing in non-vital immature permanent teeth: a review. Br Dent J. 1997; 183: 241–6. DOI: https://doi.org/10.1038/sj.bdj.4809477

Andreasen J, Farik B, Munksgaard E. Long-term calcium hydroxide as a root canal dressing may increase risk of root fracture. Dent Traumatol. 2002; 18: 134–7. DOI: https://doi.org/10.1034/j.1600-9657.2002.00097.x

Parirokh M, Torabinejad M. Mineral Trioxide Aggregate: A Comprehensive Literature Review-Part III: Clinical Applications, Drawbacks, and Mechanism of Action. J Endod. 2010; 36: 400–13. DOI: https://doi.org/10.1016/j.joen.2009.09.009

Modena K, Casas-Apayco L, Atta M, Costa C, Hebling J, Sipert C, et al. Cytotoxicity and biocompatibility of direct and indirect pulp capping materials. J Appl Oral Sci. 2009; 17: 544–54. DOI: https://doi.org/10.1590/S1678-77572009000600002

Bajwa N, Jingarwar M, Pathak A. Single Visit Apexification Procedure of a Traumatically Injured Tooth with a Novel Bioinductive Material (Biodentine). Int J Clin Pediatr Dent. 2015; 8: 58–61. DOI: https://doi.org/10.5005/jp-journals-10005-1284

Sato I, Kota K, Iwaku M, Hoshino E. Sterilization of infected root-canal dentine by topical application of a mixture of ciprofloxacin, metronidazole and minocycline in situ. Int Endod J. 1996; 29: 118–24. DOI: https://doi.org/10.1111/j.1365-2591.1996.tb01172.x

Trope M. Regenerative potential of dental pulp. Pediatr Dent. 2008; 30: 206–10. DOI: https://doi.org/10.1016/j.joen.2008.04.001

Huang G. A paradigm shift in endodontic management of immature teeth: Conservation of stem cells for regeneration. J Dent. 2008; 36: 379–86. DOI: https://doi.org/10.1016/j.jdent.2008.03.002

Cvek M. Prognosis of luxated non-vital maxillary incisors treated with calcium hydroxide and filled with gutapercha. Dent Traumatol. 1992; 8: 45–55. DOI: https://doi.org/10.1111/j.1600-9657.1992.tb00228.x

Kim S, Malek M, Sigurdsson A, Lin L, Kahler B. Regenerative endodontics: a comprehensive review. Int Figure 5. Cvek’s classification of root development10www.sada.co.za / SADJ Vol. 76 No. 9Endod J. 2018; 51: 1367–88. DOI: https://doi.org/10.1111/iej.12954

Kontakiotis E, Filippatos C, Agrafioti A. Levels of evidence for the outcome of regenerative endodontic therapy. J Endod. 2014; 40: 1045–53. DOI: https://doi.org/10.1016/j.joen.2014.03.013

Soares J, Santos S, Silveira F, Nunes E. Nonsurgical treatment of extensive cyst-like periapical lesion of endodontic origin. Int Endod J. 2006; 39: 566–75. DOI: https://doi.org/10.1111/j.1365-2591.2006.01109.x

Hoshino E, Kurihara-Ando N, Sato I, Uematsu H, Sato M, Kota K, et al. In-vitro antibacterial susceptibility of bacteria taken from infected root dentine to a mixture of ciprofloxacin, metronidazole and minocycline. Int Endod J. 1996; 29: 125–30. DOI: https://doi.org/10.1111/j.1365-2591.1996.tb01173.x

Madhubala M, Srinivasan N, Ahamed S. Comparative Evaluation of Propolis and Triantibiotic Mixture as an Intracanal Medicament against Enterococcus faecalis. J Endod. 2011; 37: 1287–9. DOI: https://doi.org/10.1016/j.joen.2011.05.028

Er K, Kuştarci A, Özan Ü, Taşdemir T. Nonsurgical Endodontic Treatment of Dens Invaginatus in a Mandibular Premolar with Large Periradicular Lesion: A Case Report. J Endod. 2007; 33: 322–4. DOI: https://doi.org/10.1016/j.joen.2006.09.001

Kusgoz A, Yildirim T, Er K, Arslan I. Retreatment of a Resected Tooth Associated with a Large Periradicular Lesion by Using a Triple Antibiotic Paste and Mineral Trioxide Aggregate: A Case Report with a Thirty-month Follow-up. J Endod. 2009; 35: 1603–6. DOI: https://doi.org/10.1016/j.joen.2009.07.019

Vidal K, Martin G, Lozano O, Salas M, Trigueros J, Aguilar G. Apical Closure in Apexification: A Review and Case Report of Apexification Treatment of an Immature Permanent Tooth with Biodentine. J Endod. 2016; 42: 730–4. DOI: https://doi.org/10.1016/j.joen.2016.02.007

Rosenberg P, Frisbie J, Lee J, Lee K, Frommer H, Kottal S, et al. Evaluation of Pathologists (Histopathology) and Radiologists (Cone Beam Computed Tomography) Differentiating Radicular Cysts from Granulomas. J Endod. 2010; 36: 423–8. DOI: https://doi.org/10.1016/j.joen.2009.11.005

Simon J, Enciso R, Malfaz J, Roges R, Bailey-Perry M, Patel A. Differential Diagnosis of Large Periapical Lesions Using Cone-Beam Computed Tomography Measurements and Biopsy. J Endod. 2006; 32: 833–7. DOI: https://doi.org/10.1016/j.joen.2006.03.008

Sharma S, Sharma V, Passi D, Srivastava D, Grover S, Dutta S. Large Periapical or Cystic Lesions in Association with Roots Having Open Apices Managed Nonsurgically Using 1-step Apexification Based on Platelet-rich Fibrin Matrix and Biodentine Apical Barrier: A

Case Series. J Endod. 2018; 44: 179–85.

Downloads

Published

2021-10-29

How to Cite

Resolution of a large periapical lesion in an immature maxillary lateral incisor with the aid of triple antibiotic paste. (2021). South African Dental Journal, 76(09), 560-564. https://doi.org/10.17159/2519-0105/2021/v76no9a7