Spindle cell carcinoma of the lower lip: A case report and review of the literature
DOI:
https://doi.org/10.17159/sadj.v79i05.18054Keywords:
Histopathological, cytokeratinAbstract
To document the lip as an unusual site of clinical presentation of spindle cell carcinoma and to conduct a review of the literature. A 66-year-old male patient presented with an ulcerated lesion of the lower lip. Morphological examination and immunohistochemical profiling of the lesion were performed.
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Lewis JS, Jr. Spindle cell lesions – neoplastic or non-neoplastic?: spindle cell carcinoma and other atypical spindle cell lesions of the head and neck. Head Neck Pathol. Jun 2008;2(2):103-110
Varshini M, Salian V, Shetty P, Krishnan S. Spindle cell carcinoma in the maxilla: A rare case and literature review. Dent Res J (Isfahan). Jan-Feb 2019;16(1):60-63
Colney L, Panigrahi C, Sultania M, Adhya AK. Second Primary Spindle Cell Carcinoma of the Tongue: A Rare Histology. Cureus. Jul 2022;14(7):e27175
Lee ET. A spindle cell squamous cell carcinoma on the cheek presenting with in transit metastases and a satellite lesion. Arch Craniofac Surg. Feb 2020;21(1):58-63
Zhang B, Xiao Q, Yang D, et al. Spindle cell carcinoma of the esophagus: A multicenter analysis in comparison with typical squamous cell carcinoma. Medicine (Baltimore). Sep 2016;95(37):e4768
Samuel S, Sreelatha SV, Hegde N, Nair PP. Spindle cell carcinoma in maxilla. BMJ Case Rep. Apr 30 2013;2013
Tehrani MJ, Rashidinia A, Amoli FA, Esfandiari A. A rare presentation of orbital spindle cell carcinoma a case report and brief review of the literature. BMC Ophthalmol. Sep 8 2023;23(1):369
Alem HB, AlNoury MK. Management of spindle cell carcinoma of the maxillary sinus: a case report and literature review. Am J Case Rep. Oct 24 2014;15:454-458
Watson RF, Chernock RD, Zhang KH, et al. Epidermal Growth Factor Receptor Expression in Spindle Cell Carcinomas of the Head and Neck. Head Neck Pathol. Sep 2015;9(3):360-368
Iqbal MS, Paleri V, Brown J, et al. Spindle cell carcinoma of the head and neck region: treatment and outcomes of 15 patients. Ecancermedicalscience. 2015;9:594
Feng L, Cai D, Muhetaer A, et al. Spindle cell carcinoma: the general demographics, basic clinico-pathologic characteristics, treatment, outcome and prognostic factors. Oncotarget. Jun 27 2017;8(26):43228-43236
Oktay M, Kokenek-Unal TD, Ocal B, Saylam G, Korkmaz MH, Alper M. Spindle cell carcinoma of the tongue: a rare tumor in an unusual location. Patholog Res Int. Feb 20 2011;2011:572381
Ramamurti A, Venkataraman M, Narasimhan M, Rao SR. Spindle cell carcinoma of the gingiva: A rare occurrence. Contemp Clin Dent. Oct 2013;4(4):500-503
Patankar SR, Gaonkar PP, Bhandare PR, Tripathi N, Sridharan G. Spindle Cell Carcinoma of the Mandibular Gingiva - A Case Report. J Clin Diagn Res. Feb 2016;10(2):ZD08-10
Biradar MV, Dantkale SS, Abhange RS, Kamra HT, Birla K. Spindle cell carcinoma of the tongue: a rare variant of squamous cell carcinoma. Ecancermedicalscience. 2014;8:447
Chamoli A, Gosavi AS, Shirwadkar UP, et al. Overview of oral cavity squamous cell carcinoma: Risk factors, mechanisms, and diagnostics. Oral Oncol. Oct 2021;121:105451
Zheng Y, Xiao M, Tang J. Clinicopathological and immunohistochemical analysis of spindle cell carcinoma of the larynx or hypopharynx: A report of three cases. Oncol Lett. Aug 2014;8(2):748-752
Goncalves PH, Montezuma-Rusca JM, Yarchoan R, Uldrick TS. Cancer prevention in HIV-infected populations. Semin Oncol. Feb 2016;43(1):173-188
Thompson LDR. Squamous cell carcinoma variants of the head and neck. Current Diagnostic Pathology. 2003;9:384-396
Mardi K, Singh N. Acantholytic squamous cell carcinoma of the oral cavity: A rare entity. J Oral Maxillofac Pathol. Sep 2014;18(Suppl 1):S128-130
Yadav S, Bal M, Rane S, Mittal N, Janu A, Patil A. Carcinoma Cuniculatum of the Oral Cavity: A Series of 6 Cases and Review of Literature. Head Neck Pathol. Mar 2022;16(1):213-223
Viswanathan S, Rahman K, Pallavi S, et al. Sarcomatoid (spindle cell) carcinoma of the head and neck mucosal region: a clinicopathologic review of 103 cases from a tertiary referral cancer centre. Head Neck Pathol. Dec 2010;4(4):265-275
Xu M, Zhang T, Xia R, Wei Y, Wei X. Targeting the tumor stroma for cancer therapy. Mol Cancer. Nov 2 2022;21(1):208
Debnath P, Huirem RS, Dutta P, Palchaudhuri S. Epithelial-mesenchymal transition and its transcription factors. Biosci Rep. Jan 28 2022;42(1)
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