Spindle cell carcinoma of the lower lip: A case report and review of the literature
DOI:
https://doi.org/10.17159/sadj.v79i05.18054Keywords:
Histopathological, cytokeratinAbstract
To document the lip as an unusual site of clinical presentation of spindle cell carcinoma and to conduct a review of the literature. A 66-year-old male patient presented with an ulcerated lesion of the lower lip. Morphological examination and immunohistochemical profiling of the lesion were performed.
Downloads
Metrics
References
Lewis JS, Jr. Spindle cell lesions – neoplastic or non-neoplastic?: spindle cell carcinoma and other atypical spindle cell lesions of the head and neck. Head Neck Pathol. Jun 2008;2(2):103-110
Varshini M, Salian V, Shetty P, Krishnan S. Spindle cell carcinoma in the maxilla: A rare case and literature review. Dent Res J (Isfahan). Jan-Feb 2019;16(1):60-63
Colney L, Panigrahi C, Sultania M, Adhya AK. Second Primary Spindle Cell Carcinoma of the Tongue: A Rare Histology. Cureus. Jul 2022;14(7):e27175
Lee ET. A spindle cell squamous cell carcinoma on the cheek presenting with in transit metastases and a satellite lesion. Arch Craniofac Surg. Feb 2020;21(1):58-63
Zhang B, Xiao Q, Yang D, et al. Spindle cell carcinoma of the esophagus: A multicenter analysis in comparison with typical squamous cell carcinoma. Medicine (Baltimore). Sep 2016;95(37):e4768
Samuel S, Sreelatha SV, Hegde N, Nair PP. Spindle cell carcinoma in maxilla. BMJ Case Rep. Apr 30 2013;2013
Tehrani MJ, Rashidinia A, Amoli FA, Esfandiari A. A rare presentation of orbital spindle cell carcinoma a case report and brief review of the literature. BMC Ophthalmol. Sep 8 2023;23(1):369
Alem HB, AlNoury MK. Management of spindle cell carcinoma of the maxillary sinus: a case report and literature review. Am J Case Rep. Oct 24 2014;15:454-458
Watson RF, Chernock RD, Zhang KH, et al. Epidermal Growth Factor Receptor Expression in Spindle Cell Carcinomas of the Head and Neck. Head Neck Pathol. Sep 2015;9(3):360-368
Iqbal MS, Paleri V, Brown J, et al. Spindle cell carcinoma of the head and neck region: treatment and outcomes of 15 patients. Ecancermedicalscience. 2015;9:594
Feng L, Cai D, Muhetaer A, et al. Spindle cell carcinoma: the general demographics, basic clinico-pathologic characteristics, treatment, outcome and prognostic factors. Oncotarget. Jun 27 2017;8(26):43228-43236
Oktay M, Kokenek-Unal TD, Ocal B, Saylam G, Korkmaz MH, Alper M. Spindle cell carcinoma of the tongue: a rare tumor in an unusual location. Patholog Res Int. Feb 20 2011;2011:572381
Ramamurti A, Venkataraman M, Narasimhan M, Rao SR. Spindle cell carcinoma of the gingiva: A rare occurrence. Contemp Clin Dent. Oct 2013;4(4):500-503
Patankar SR, Gaonkar PP, Bhandare PR, Tripathi N, Sridharan G. Spindle Cell Carcinoma of the Mandibular Gingiva - A Case Report. J Clin Diagn Res. Feb 2016;10(2):ZD08-10
Biradar MV, Dantkale SS, Abhange RS, Kamra HT, Birla K. Spindle cell carcinoma of the tongue: a rare variant of squamous cell carcinoma. Ecancermedicalscience. 2014;8:447
Chamoli A, Gosavi AS, Shirwadkar UP, et al. Overview of oral cavity squamous cell carcinoma: Risk factors, mechanisms, and diagnostics. Oral Oncol. Oct 2021;121:105451
Zheng Y, Xiao M, Tang J. Clinicopathological and immunohistochemical analysis of spindle cell carcinoma of the larynx or hypopharynx: A report of three cases. Oncol Lett. Aug 2014;8(2):748-752
Goncalves PH, Montezuma-Rusca JM, Yarchoan R, Uldrick TS. Cancer prevention in HIV-infected populations. Semin Oncol. Feb 2016;43(1):173-188
Thompson LDR. Squamous cell carcinoma variants of the head and neck. Current Diagnostic Pathology. 2003;9:384-396
Mardi K, Singh N. Acantholytic squamous cell carcinoma of the oral cavity: A rare entity. J Oral Maxillofac Pathol. Sep 2014;18(Suppl 1):S128-130
Yadav S, Bal M, Rane S, Mittal N, Janu A, Patil A. Carcinoma Cuniculatum of the Oral Cavity: A Series of 6 Cases and Review of Literature. Head Neck Pathol. Mar 2022;16(1):213-223
Viswanathan S, Rahman K, Pallavi S, et al. Sarcomatoid (spindle cell) carcinoma of the head and neck mucosal region: a clinicopathologic review of 103 cases from a tertiary referral cancer centre. Head Neck Pathol. Dec 2010;4(4):265-275
Xu M, Zhang T, Xia R, Wei Y, Wei X. Targeting the tumor stroma for cancer therapy. Mol Cancer. Nov 2 2022;21(1):208
Debnath P, Huirem RS, Dutta P, Palchaudhuri S. Epithelial-mesenchymal transition and its transcription factors. Biosci Rep. Jan 28 2022;42(1)
Downloads
Published
How to Cite
Issue
Section
License
![Creative Commons License](http://i.creativecommons.org/l/by-nc/4.0/88x31.png)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.