The head and neck features of Gardner’s Syndrome: A case report and review of the literature

Authors

  • AI Black Department of Maxillofacial and  Oral Radiology, School of Oral Health Sciences, Sefako Makgatho  Health Sciences University, Pretoria, South Africa
  • BK Bunn Department  of Operative Dentistry, School of Oral Health Sciences, Sefako  Makgatho Health Sciences University, Pretoria, South Africa
  • PD Motloba Department of  Community Dentistry, School of Oral Health Sciences, Sefako  Makgatho Health Sciences University, Pretoria, South Africa
  • P Gwengu Department of Operative Dentistry, School of Oral Health  Sciences, Sefako Makgatho Health Sciences University, Pretoria,  South Africa

DOI:

https://doi.org/10.17159/sadj.79i06.18335

Keywords:

Gardner’s Syndrome, osteomas, intestinal polyposis, odontomas, supernumerary teeth, epidermoid cysts

Abstract

Gardner’s Syndrome represents an autosomal dominant variant of Familial Adenomatous Polyposis in which affected individuals have a 100% risk of developing colorectal carcinoma. The extra-intestinal manifestations in the head and neck region allow for the early recognition and diagnosis of this rare syndrome. The defining triad of features includes intestinal polyposis, dento-osseous 
anomalies and soft tissue lesions. 

A 20-year-old female patient presented with a main complaint of swelling involving the left side of her nose, at which time a panoramic radiograph was obtained.

Radiographic findings showed multiple osteomas, odontomas, missing teeth as well as unerupted and impacted teeth, the features of which are highly suggestive of Gardner’s Syndrome. 

Early recognition of the extra-intestinal features of Gardner’s Syndrome warrants patient referral for further investigation 
including colonoscopy and genetic testing

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Author Biography

  • P Gwengu, Department of Operative Dentistry, School of Oral Health  Sciences, Sefako Makgatho Health Sciences University, Pretoria,  South Africa




References

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Published

2024-10-18

Issue

Vol. 79 No. 07 (2024): The South African Dental Journal

Section

Case Reports

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite

Black, A., Bunn, B., Motloba, P., & Gwengu, P. (2024). The head and neck features of Gardner’s Syndrome: A case report and review of the literature. South African Dental Journal, 79(07), 387-390. https://doi.org/10.17159/sadj.79i06.18335