Sodium hypochlorite as an endodontic irrigant and its effect on dentine: a review of literature
DOI:
https://doi.org/10.17159/sadj.v78i10.16545Keywords:
Sodium hypochlorite, dentine, endodontic irrigantAbstract
Successful endodontic treatment is achieved by a combination of factors which include acceptable instrumentation, optimal irrigation and disinfection of the root canal system. It is vital that a suitable antimicrobial agent be used during irrigation and sodium hypochlorite emerges as the optimal agent to be used as it complies with most of the criteria of an ideal irrigant. Sodium hypochlorite
is a popular choice as an endodontic irrigant due to its solvent activity as well as its antimicrobial action. The tissue dissolving ability of sodium hypochlorite depends on its concentration, volume, contact time of solution with tissue remnants, refreshment and/or activation cycles of solution, as well as the surface area of exposed tissue
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References
Torabinejad M, Walton RE. Endodontics Principles and Practice, 4th ed. St. Louis: Saunders, 2009: 264-265
Albahiti MH. Knowledge and practices of decontamination during root canal treatment by dentists in Jeddah. Saudi Dent J. 2020; 32(4): 213-218
Khandelwal A, Janani K, Teja K, Jose J, Battineni G, Riccitiello F, Valletta A, Palanivelu A, Spagnuolo G. Periapical Healing following Root Canal Treatment Using Different Endodontic Sealers: A Systematic Review. Biomed Res Int. 2022; (8): 1-9c'
de Souza RA, de Castro FP, Pires OJ. Research of the major methods and clinical outcomes of irrigation in endodontics: a systematic review. J Health Med Sci. 2022; 15(3): 1-5
Raducka M, Piszko A, Piszko PJ, Jawor N, Dobrzynski M, Grzebieluch W, Mikulewicz M, Skoskiewicz-Malinowska K. Narrative review on methods of activating irrigation liquids for root canal treatment. Appl Sci. 2023; 30(13):7733
Estrela C, Estrela CRA, Barbin EL, Spanó JCE, Marchesan MA, Pécora JD. 2002. Mechanism of action of sodium hypochlorite. Braz Dent J. 2002; 13(2): 113-117
Paixão S, Rodrigues C, Grenho L, Fernandes MH. Efficacy of sonic and ultrasonic activation during endodontic treatment: A Meta-analysis of in vitro studies. Acta Odontol Scand. 2022; 80(8):588-595
Moukarab, DAA. Evaluation of antimicrobial activity of manually agitate (nano chitosan and nano-propolis) against Enterococcus faecalis in comparison with sodium hypochlorite: an in-vitro study. Egypt Dent J. 2020; 66(1):587-596
Young GR, Parashos P, Messer HH. The principles of techniques for cleaning root canals. Aust Dent J. 2007; 52(1): S52-S63
Baugh D, Wallace J. The role of apical instrumentation in root canal treatment: A review of the literature. J Endod. 2005; 31(5): 333-340
Abraham S, Raj JD, Venugopal M. Endodontic irrigants: A comprehensive review. J Pharm Sci Res. 2015; 7(1):5
Topcu KM, Karatas E, Ozsu D, Ersoy I. Efficiency of the Self Adjusting File, WaveOne, Reciproc, ProTaper and handfiles in root canal debridement. Eur J of Dent. 2014; 8(3):326-329
Gulabivala K, Patel B, Evans G, Ng Y-L. Effects of mechanical and chemical procedures on root canal surfaces. Endod Topics. 2005; 10(1): 103-122
Li Q, Zhang Q, Zou X, Yue L. Evaluation of four final irrigation protocols for cleaning root canal walls. Int J Oral Sci. 2020; 12(1):29
Slutzky-Goldberg I, Hanut A, Matalon S, Baev V, Slutzky H. The effect of dentin on the pulp tissue dissolution capacity of sodium hypochlorite and calcium hydroxide. J Endod. 2013; 39(8): 980-983
Ruksakiet K, Hanák L, Farkas N, Hegyi P, Sadaeng W, Czumbel LM, Sang-Ngoen T, Garami A, Mikó A, Varga G, Lohinai Z. Antimicrobial efficacy of chlorhexidine and sodium hypochlorite in root canal disinfection: a systematic review and meta analysis of randomized controlled trials. J Endod. 2020; 46(8):1032-41
Karunakaran JV, Kumar SS, Kumar M, Chandrasekhar S, Namitha D. The effects of various irrigating solutions on intra-radicular dentinal surface: A SEM analysis. J Pharm BioAllied Sci. 2012; 4(6): 125-130
Wu D, Ma YZ, Jia J, Xin BC, Wang DS, Sun DG, Wang LX. Removal of the root canal smear layer using Carisolv III and sodium hypochlorite. J Med. 2020; 99(22): e20372
Oliveira LD, Carvalho CAT, Nunes W, Valera MC, Carmango CHR, Jorge AOC, dos Campos SJ. Effects of chlorhexidine and sodium hypochlorite on the microhardness of root canal dentin. Oral Surg Oral Med Oral Pathol Oral Radiol. 2007; 104(4):
e125-e128
Mohammadi Z. Sodium hypochlorite in endodontics: an update review. Int Dent J. 2008; 58(6): 329-341
Moorer WR, Wesselink PR. Factors promoting the tissue dissolving capability of sodium hypochlorite. Int Endod J. 1982; 15(4): 187-196
Zehnder M. Root canal irrigants. J Endod. 2006; 32(5): 389-398
Haapasalo M, Shen Y, Wang Z, Gao Y. Irrigation in endodontics. Br Dent J. 2014; 216(6): 299-303
De-Deus G, Garcia-Filho P. Influence of the NiTi rotary system on the debridement quality of the root canal space. Oral Surg Oral Med Oral Pathol Radiol. 2009; 108(4): e71-e76
Kaur P. Role of Irrigants in Endodontics. J dent problems solutions. 2020; 9(7):100-4
Ghorbanzadeh S, Loodaricheh SA, Samizade S, Zadsirjan S. Irrigants in endodontic treatment. Int j contemp dent med rev. 2015; 11: p12
Macedo RG, Verhaagen B, Wesselink PR, Versluis M, Van Der Sluis LWM. 2014. Influence of refreshment/activation cycles and temperature rise on the reaction rate of sodium hypochlorite with bovine dentine during ultrasonic activated irrigation. Int Endod J. 2014; 47(2): pp.147-154
Zou L, Shen Y, Li W, Haapasalo M. Penetration of sodium hypochlorite into dentine. J Endod. 2010; 36(5): 793-796
Wong DT, Cheung GS. Extension of bactericidal effect of sodium hypochlorite into dentinal tubules. J Endod. 2014; 40(6): 825-829
Trautmann E, Attin T, Mohn D, Zehnder M. Hydrogen peroxide versus sodium hypochlorite: all a matter of pH? J Endod. 2021; 47(2): 297-302
Srinivasan S, Kumarappan SK, Ramachandran A, Honap MN, Kadandale S, Rayar S. Comparative evaluation of pulp tissue dissolution ability of sodium hypochlorite by various activation techniques: An in vitro study. J Conserv Dent. 2020; 23(3): 304
Petridis X, Busanello FH, So MV, Dijkstra RJ, Sharma PK, van der Sluis LW. Factors affecting the chemical efficacy of 2% sodium hypochlorite against oral steady-state dual-species biofilms: Exposure time and volume application. Int Endod J. 2019; 52(8):1182-95
Kandaswamy D, Venkateshbabu N. Root canal irrigants. J Conserv Dent. 2010; 13(4): 256-264
Sirtes G, Waltimo T, Schaetzle M, Zehender M. The effects of temperature on sodium hypochlorite short-term stability, pulp dissolution capacity, and antimicrobial efficacy. J Endod. 2005; 31(9): 669-671
Yared G, Ramli GA. Antibacterial ability of sodium hypochlorite heated in the canals of infected teeth: An ex vivo study. Cureus. 2020; 12(2): 1-6
Iandolo A, Abdellatif D, Amato M, Pantaleo G, Blasi A, Franco V, Neelakantan P, Clarkson RM, Moule AJ, Podlich HM. The shelf-life of sodium hypochlorite irrigating solutions. Aust Dent J. 2001; 46(4): pp.269-276
Paragliola R, Franco V, Fabiani C, Mazzoni A, Nato F, Tay FR, Breschi L, Grandini S. Final rinse optimization: influence of different agitation protocols. J Endod. 2010; 36(2): 282-285
Al-Ali M, Sathorn C, Parashos P. Root canal debridement efficacy of different final irrigation protocols. Int Endod J. 2012; 45(10): 898-906
Aveiro E, Chiarelli-Neto VM, de-Jesus-Soares A, Zaia AA, Ferraz CC, Almeida JF, Marciano MA, Feres M, Gomes BP. Efficacy of reciprocating and ultrasonic activation of 6% sodium hypochlorite in the reduction of microbial content and virulence factors in teeth with primary endodontic infection. Int Endod J. 2020; 53(5):604-18
Wahjuningrum DA, Kandow R, Rulianto M, Prayogo K. Irrigation solution pattern in root canal treatment (Irrigation solution pattern in root canal between negative pressure system by Endovac and sonic activation by Eddy System). J Int Dent Med Res. 2020; 13(1): pp.111-115
Arvaniti IS, Khabbaz MG. Influence of root canal taper on its cleanliness: A scanning electronic microscopic study. J Endod. 2011; 37(6): 871-874
Basudan, S.O. Sodium hypochlorite use, storage, and delivery methods: A Survey. Saudi Endod J. 2019; 9(1): pp.27-33
Sassone LM, Fidel RA, Murad CF, Fidel SR, Hirata Jr R. Antimicrobial activity of sodium hypochlorite and chlorhexidine by two different tests. Aust Endod J. 2008; 34(1): 19-24
Ferraz CC, Gomes BP, Zaia AA, Teixeira FB, Souza-Filho FJ. Comparative study of the antimicrobial efficacy of chlorhexidine gel,chlorhexidine solution and sodium hypochlorite as endodontic irrigants. Braz Dent J. 2007; 18(4): 294-8
Siqueira JF, Rôças IN, Favieri A, Lima KC. Chemomechanical reduction of the bacterial population in the root canal after instrumentation and irrigation with 1%, 2.5%, and 5.25% sodium hypochlorite. J Endod. 2000; 26(6): 331-4
Retamozo BR, Shabahang S, Johnson N, Aprecio RM, Torabinejad M. Minimum contact time and concentration of sodium hypochlorite required to eliminate Enterococcus faecalis. J Endod. 2010; 36(3): 520-523
Du T, Wang Z, Shen Y, Ma J, Cao Y, Haapasalo M. Effect of long-term exposure to endodontic disinfecting solutions on young and old Enterococcus faecalis biofilms in dentin canals. J Endod. 2014; 40(4): 509-14
Pascon FM, Kantovitz KR, Sacramento PA, Nobre-dos-Santos M, Puppin-Rontani RM. Effect of sodium hypochlorite on dentine mechanical properties. A review. J Dent. 2009; 37(12): 903-908
Grigoratos D, Knowles J, Ng YL, Gulabivala K. Effect of exposing dentine to sodium hypochlorite and calcium hydroxide on its flexural strength and elastic modulus. Int Endod J. 2001; 34(2): 113-9
Marending M, Luder HU, Brunner TJ, Knecht S, Stark WJ, Zehnder M. Effect of sodium hypochlorite on human root dentine- mechanical, chemical and structural evaluation. Int Endod J. 2007; 40(10): 786-93
Aslantas EE, Buzoglu HD, Altundasar E, Serper A. Effect of EDTA, sodium hypochlorite, and chlorhexidine gluconate with or without surface modifiers on dentine microhardness. J Endod. 2014; 40 (6): 876-9
Ari H, Erdemir A, Belli S. Evaluation of the effect of endodontic irrigation solutions on the microhardness and the roughness of root canal dentin. J Endod. 2004; 30(11): 792-5
Kumar, G.A. and Anita, G. Evaluation of the Effect of EDTA, EGTA and Citric Acid on the Microhardness and Roughness of Human Radicular Dentin-An In Vitro Study. Natl J Integr Res Med. 2014; 5(6):24-30
Ulusoy OÌA, Görgül G. 2013. Effects of different irrigation solutions on root dentine microhardness, smear layer removal and erosion. Aust Endod J. 2013; 39(2): 66-72
Slutzky-Goldberg I, Maree M, Liberman R, Heling I. Effect of sodium hypochlorite on dentin microhardness. J Endod. 2004; 30(12): 880-2
Tartari T, Silva e Souza Pd-AR, de Almeida BVN, Silva Júnior JOC, Pessoa OF, Silva e Sousa Junior MH. A new weak chelator in endodontics: Effects of different irrigation regimens with Etidronate on root dentin microhardness. Int J Dent. 2013; 1-6
Sim TPC, Knowles JC, Ng YL, Shelton J, Gulabiwala K. Effect of sodium hypochlorite on mechanical properties of dentine and tooth surface strain. Int Endod J. 2001; 34(2): 120-132
Butt N, Talwar S.In-vitro evaluation of various solvents for retrieval of mineral trioxide aggregate and their effects on microhardness of dentine. J Conserv Dent. 2013; 16(3): 199-202
Zaparolli D, Saquy PC, Cruz-Filho AM. Effect of sodium hypochlorite and EDTA irrigation, individually and in alternation, on dentine microhardness at the furcation area of mandibular molars. Braz Dent J. 2012; 23(6): 654-8
Marending M, Paqué F, Fischer J, Zehnder M. Impact of irrigant sequence on mechanical properties of human root dentin. J Endod. 2007; 33(11): 1325-28
Hart PS, Hart TC. Disorders of human dentin. Cells Tissues Organs. 2007; 186(1): pp.70-77
John C, Löst C, Elayouti A. Ultrasonic monitoring of the effect of sodium hypochlorite on the elasticity of dentine. Int Endod J. 2013; 46(5): 477-482
Sobhani OE, Gulabiwala K, Knowles J, Ng Y-L. The effect of irrigation time, root morphology and dentine thickness on tooth surface strain when using 5% sodium hypochlorite and 17% EDTA. Int Endod J. 2010; 43(3): 190-199
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