Paediatric Inflammatory Multisystem Syndrome associated with Covid-19 infection (PIMS-TS): Guidance for Oral Healthcare practitioners
Keywords:
vasculitis, respiratoryAbstract
Paediatric Inflammatory Multisystem Syndrome temporally associated with SARS-CoV-2 infection (PIMS-TS) has been reported globally since the outbreak of the coronavirus disease. The syndrome shares similarities with Kawasaki disease (KD). The manifestation of oral changes in both PIMS-TS and KD warrants that the oral health practitioner has an awareness of these conditions to facilitate timely
management.
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Arentz M, Yim E, Klaff L, et al. Characteristics and Outcomes of 21 Critically Ill Patients With COVID-19 in Washington State. JAMA. 2020; 323(16).1612-14
Rybkina K, Bell JN, Bradley MC, et al. SARS-CoV-2 infection and recovery in children: Distinct T cell responses in MIS-C compared to COVID-19. J Exp Med. 2023; 220(8):1-19
Deza Leon MP, Redzepi A, McGrath E, et al. COVID-19-associated pediatric multisystem inflammatory syndrome. J Pediatric Infect Dis Soc 2020;9(3):407-8
Cattalini M, Della Paolera S, Zunica F, Bracaglia C, Giangreco M, Verdoni L, et al. Defining Kawasaki disease and pediatric inflammatory multisystem syndrome temporally associated to SARS-CoV-2 infection during SARS-CoV-2 epidemic in Italy: results from a national, multicenter survey. Pediatric Rheumatology. 2021; 19(1):19-29
Hoste L, Van Paemel R, Haerynck F. (2021). Multisystem inflammatory syndrome in children related to COVID-19: a systematic review. Eur J Pediatr. 2021; 180(7): 2019-2034 https://doi.org/10.1007/s00431-021-03993-5
Verdoni L, Mazza A, Gervasoni A, et al. An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study. Lancet. 2020; 395:1771-8
Holman RC, Belay ED, Christensen KY, et al. Hospitalizations for Kawasaki syndrome among children in the United States, 1997-2007. Pediatr Infect Dis J. 2010;29:483-8 doi: 10.1097/INF.0b013e3181cf8705
McCrindle BW, Manlhiot C. SARS-CoV-2-related inflammatory multisystem syndrome in children. JAMA. 2020;40(1):35-42 202 > REVIEW
Shulman ST, Rowley AH. Kawasaki disease: insights into pathogenesisand approaches to treatment. Nat. Rev. Rheumatol. 2015; 11: 475-482
Nakamura Y. Kawasaki disease: epidemiology and the lessons from it. Int J Rheum Dis. 2018; 21: 16-19 https://doi.org/10.1111/1756-185X.13211
Rowley AH, Shulman ST. The Epidemiology and Pathogenesis of Kawasaki Disease. Front Pediatr. 2018;6:374
McCrindle BW, Rowley AH, Newburger JW, et al. Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Scientific Statement for Health Professionals From the American Heart Association. Circulation. 2017;135 (17); e927-e999 https://www.ahajournals.org/doi/pdf/10.1161/CIR.0000000000000484
Kim JH, Yu JJ, Lee J, et al. Detection rate and clinical impact of respiratory viruses in children with Kawasakidisease.KoreanJ Pediatr.2012;55:470-473. doi:10.3345/kjp.2012.55.12.470
Benseler SM, McCrindle BW, Silverman ED, et al. Infections and Kawasaki disease: implications for coronary artery outcome. Pediatrics. 2005;116: e760-e766.
Turnier JL, Anderson MS, Heizer HR, et al. Concurrent respiratory viruses and Kawasaki disease. Pediatrics. 2015;136: e609-e614. doi: 10.1542/ peds.2015-0950
Jaggi P, Kajon AE, Mejias A, et al. Human adenovirus infection in Kawasaki disease: a confounding bystander? Clin Infect Dis. 2013; 56:58-64. doi: 10.1093/cid/cis807
Schlapbach LJ, Andre MC, Grazioli S, et al. PIMS-TS working group of the Interest Group for Pediatric Neonatal Intensive Care (IGPNI) of the Swiss Society of Intensive Care and the Pediatric Infectious Diseases Group Switzerland (PIGS). Best Practice Recommendations for the Diagnosis and Management of Children With Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2
(PIMS-TS; Multisystem Inflammatory Syndrome in Children, MIS-C) in Switzerland. Front Pediatr. 2021; 9. doi: 10.3389/fped.2021.667507
Belhadjer Z, Méot M, Bajolle F, et al. Acute heart failure in multisystem inflammatory syndrome in children (MIS-C) in the context of global SARS-CoV-2 pandemic. Circulation. 2020;142(5):429-436
Verdoni L, Mazza A, Gervasoni A, et al. An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study. Lancet. 2020;395(10239):1771-1778
Pouletty M, Borocco C, Ouldali N, et al. Paediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 mimicking Kawasaki disease (Kawa-COVID-19): A multicentre cohort. Ann Rheum Dis 2020;79(8):999-1006 https://doi.org/10.1136/annrheumdis-2020-217960
Cheung EW, Zachariah P, Gorelik M, et al. Multisystem inflammatory syndrome related to COVID-19 in previously healthy children and adolescents in New York City. JAMA. 2020;324(3):294
Whittaker E, Bamford A, Kenny J, et al. Clinical characteristics of 58 children with a pediatric inflammatory multisystem syndrome temporally associated with SARSCoV-2. JAMA.2020;324(3):259-269
Kaur G, Gupta J, Verma L, Passi S, Joshi M. Recurrent Kawasaki Disease presenting to dentists: “Think Beyond Dentition”. Int J Clin Pediatr Dent. 2018;11(6):535
Fukushige J, Takahashi N, Ueda Y, Ueda K. Incidence and clinical features of incomplete Kawasaki disease. Acta Paediatr. 1994; 83(10):1057-1060
Whittaker E, Bamford A, Kenny J, et al. Clinical characteristics of 58 children with a pediatric inflammatory multisystem syndrome temporally associated with SARSCoV-2. JAMA.2020;324(3):259-269
Venkataraman A, Kumar NP, Hanna LE, et al. Plasma biomarker profiling of PIMS-TS, COVID-19 and SARS-CoV2 seropositive children - a cross-sectional observational study from southern India. EBioMedicine. 2021; 66:103317. doi:10.1016/j.ebiom.2021.103317
Harwood R, Allin B, Jones CE, Whittaker E, Ramnarayan P, Ramanan AV, Kaleem M, Tulloh R, Peters MJ, Almond S, Davis PJ. A national consensus management pathway for paediatric inflammatory multisystem syndrome temporally associated
with COVID-19 (PIMS-TS): results of a national Delphi process. The Lancet Child & Adolescent Health. 2021 Feb 1;5(2):133-41
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